What is the MLB run line?

The run line is baseball's version of a point spread, almost always set at 1.5 runs. The favorite must win by 2+ runs; the underdog can lose by 1 run or win outright. Because 1.5 runs is a small margin, the odds shift significantly: a -200 moneyline favorite might be -110 on the run line, while a +170 underdog might become -130. Run lines reward risk-takers when backing heavy favorites.